Bay of Biscay, Channel Sea, North Sea and Mediterranean Sea (Spain, Italy, Greece, Germany, Norway and France)

Bioassay and contaminant biological impact

Biological effects monitoring of chemical contaminants of the coastal marine environment of the European seas.

Akcha F., Vincent Hubert F., Pfhol-Leszkowicz A. (2003) Potential value of the comet assay and DNA adduct measurement in dab (Limanda limanda) for assessment of in situ exposure to genotoxic compounds., Mutation Research,Fundamental & Molecular Mechanisms of Mutagenesis,..., 2003, 534,21-32; Akcha F., Izuel C., Venier P., Budzinski H., Burgeot T., Narbonne J-F. (2000) Enzymatic biomarker measurement and study of DNA adduct formation in benzo[a]pyrene-contaminated mussels, Mytilus galloprovincialis., Aquat. Toxicol., 2000, 49,269-287; Ackha F, T. Burgeot, A. Leskowicz, H. Budzinski, J.F. Narbonne (2000) Induction and removal of bulky B(a)P-related DNA adducts and 8-oxodGuo in mussels Mytilus galloprovincialis exposed in vivo to B(a)P-contaminated feed., Mar. Ecol. Prog., 2000, Ser. 205,195-206 .; Burgeot T., Faucet J., Dominique M., Grosjean P. and Bocquene G. (2003) Variations of benzo(a)pyrene hydroxylase and cholinesterase activities in mussels caged in the North Sea (German Bight and Statfjord). (submitted), Environ. Toxicol and Chemistry, 2003; Burgeot T. and F. Galgani (2000) Application of EROD in marine fish in a multidisciplinary surveillance programme in the North Sea. In : Use of

biomarkers for environmental quality assessment. Editors L. Lagadic, T.

Caquet, J.C. Amiard and F. Ramade. Eds Science Publishers, Inc., 2000,33-57; Beliaeff B. and T. Burgeot (2002) Integrated biomarker response : a useful tool for ecological risk assessment., Environmental Toxicology and Chemistry, 2002, 21,1316-1322

Ifremer, Biogeochimical end Ecotoxicological Research Unit
Centre Ifremer de Nantes Rue de l'Ile d'Yeu BP 21105
NANTES CEDEX 03

44311
France